Si usted está tomando diazepam junto con otros medicamentos para controlar las convulsiones y tiene un aumento en su frecuencia o severidad, llame a su médico.
The anticonvulsant Qualities of diazepam together with other benzodiazepines can be in part or totally on account of binding to voltage-dependent sodium channels rather than GABAA receptors.
fentanyl iontophoretic transdermal system and diazepam both equally boost sedation. Keep away from or Use Alternate Drug. Limit use to clients for whom substitute remedy options are inadequate
as being a radiotracer for GABAA receptors.forty six In terms of subtype selectivity across the several subtypes
Incorrect or too much use of diazepam can result in dependence. At a particularly high hazard for diazepam misuse, material use problem or dependence are:
fosphenytoin will decrease the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
It has a now approved healthcare use in remedy in The us. Abuse could cause constrained Actual physical dependence or psychological dependence relative to All those in timetable three.
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sage decreases results of diazepam by pharmacodynamic antagonism. Slight/Significance Unfamiliar. Theoretical interaction; some species of sage may possibly cause convulsions.
diazepam will raise the degree or impact of ruxolitinib topical by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
diazepam will enhance the level or effect of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Oral: Facts not readily available No dose adjustment advisable unless administered for prolonged period; lessen dose in prolonged durations
grapefruit will boost website the amount or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Keep track of Intently (one)crofelemer boosts levels of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Crofelemer has the prospective to inhibit CYP3A4 at concentrations predicted from the intestine; not likely to inhibit systemically because minimally absorbed.